منابع مشابه
Regulation of Bone Metabolism
Bone is formed through the processes of endochondral and intramembranous ossification. In endochondral ossification primary mesenchymal cells differentiate to chondrocytes and then are progressively substituted by bone, while in intramembranous ossification mesenchymal stem cells (MSCs) differentiate directly into osteoblasts to form bone. The steps of osteogenic proliferation, differentiation,...
متن کاملInteraction between bone and glucose metabolism
Accumulating evidence has shown that bone and glucose metabolism are closely associated with each other. Since the risk of osteoporotic fractures is increased in patients with diabetes mellitus (DM), osteoporosis is recently recognized as one of diabetic complications, called DM-induced bone fragility. Previous studies showed that collagen cross-links of advanced glycation end products (AGEs) a...
متن کاملAerobic metabolism of glucose by bone.
Osseous tissue is capable of producing net amounts of lactic acid. This has been demonstrated in viva by the measurement of arteriovenous differences (2), in vitro during incubation of slices (3), and in tissue culture (4). Because direct evidence has been lacking, it has been assumed that the Embden-Meyerhof pathway is the route of lactate formation (3). Indeed, various sections of the epiphys...
متن کاملCorrelations Between Abnormal Glucose Metabolism and Bone Mineral Density or Bone Metabolism.
BACKGROUND The aim of this meta-analysis was to explore the correlations of abnormal glucose metabolism (AGM) with bone mineral density (BMD) and bone metabolism. MATERIAL/METHODS Relevant studies were identified using computerized and manual search strategies. The included studies were in strict accordance with inclusion and exclusion criteria. Statistical analyses were conducted with the Co...
متن کاملBone Regulates Glucose Metabolism as an Endocrine Organ through Osteocalcin
Skeleton was considered as a dynamic connective tissue, which was essential for mobility, calcium homeostasis, and hematopoietic niche. However more and more evidences indicate that skeleton works not only as a structural scaffold but also as an endocrine organ, which regulates several metabolic processes. Besides osteoprotegerin (OPG), sclerostin (SOST), and Dickopf (DKK) which play essential ...
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ژورنال
عنوان ژورنال: Bone
سال: 2018
ISSN: 8756-3282
DOI: 10.1016/j.bone.2017.08.008